Cocaine Use Disorder and Cortical Dopamine

You may be eligible if

• 1. Males or Females 18-40
• 2. Fulfill Diagnostic and Statistical Manual (DSM-IV) Diagnosis for Cocaine Dependence
• 3. Medically Healthy MAJOR EXCLUSIONS
• 1\. Major medical, psychiatric, co-morbid drug \& alcohol use disorders 2. Pregnancy or lactation, 3. Contraindications to MRI 4. Currently employed as radiation worker; or participation in radioactive drug research protocols within the previous year 5. Family History of a psychotic illness or manic episode in first-degree relatives
• 1. Males or Females 18-40
• 2. Absence of present or past psychiatric conditions (including alcohol or drug dependence)
• 3. A negative urine drug screen
• 4. Medically Healthy
• MAJOR EXCLUSIONS
• 1. Any medical, psychiatric, co-morbid drug \& alcohol use disorders
• 2. Pregnancy or lactation,
• 3. Contraindications to MRI
• 4. Currently employed as radiation worker; or participation in radioactive drug research protocols within the previous year
• 5. Family History of a psychotic illness or manic episode, or drug and alcohol Abuse/Dependence in first-degree relatives