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The investigators will assess the ability of ultrasound (US) to measure liver stiffness (cirrhosis) and liver fat content (steatosis).
Non-invasive monitoring of liver fibrosis using magnetic resonance imaging (MRI) can help determine which patients will most benefit from interventional therapies to help reverse the condition. Similarly, quantitative assessment of liver fat content using MRI can assist physicians in identifying patients at risk for hepatic steatohepatitis. Due to the widespread dissemination of US machines and their relative lower cost compared to other imaging modalities, e.g. MRI, the ability of US to assess these parameters widens diagnostic availability. Patients who have undergone an MRI exam to assess liver stiffness (cirrhosis) and/or liver fat content (steatosis) will be asked to undergo an US exam to assess the same parameters. The cirrhosis and steatosis measurements obtained from both exams will be compared. If US-based measurements of liver stiffness and/or liver fat content are shown to be reproducible and accurate when compared to MRI values (will be used as the gold standard), US may become the first-line diagnostic test for these liver conditions.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Stanford University Hospital
Stanford, California, United States
Stanford University
Stanford, California, United States
Start Date
August 1, 2018
Primary Completion Date
December 31, 2019
Completion Date
December 31, 2020
Last Updated
April 22, 2021
35
ACTUAL participants
Ultrasound
DIAGNOSTIC_TEST
Lead Sponsor
Stanford University
NCT06169592
NCT07275554
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