Regional Non-comparative Prospective Study of the Impact of Gamma Knife Radiosurgery on Tremor in Multiple Sclerosis

Inclusion Criteria

• •Male or female aged 18 to 70 years old.
• •Patient with a diagnosis of MS certainty according to the criteria of Mac Donald (2010)
• •Patient with progressive form of MS: remitting, secondarily progressive, primary progressive
• •Patient with an Expanded Disability Status Scale score (EDSS) between 3 and 8.
• •Patient with clinical stability for more than 6 months (EDSS stable over 1 year)
• •Lack of progressive onset (and corticosteroid therapy) for at least 3 months
• •Patient with normal palliation or mild impairment
• •Patient having a muscle test at 4 or 5 on the upper limb to be treated
• •Patient requiring Gamma-Knife radiosurgery due to severity of tremor and functional impairment
• •Patient who understood and signed the informed consent form