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COMPLETEDNA

An Open-Trial of Web-Prolonged Exposure (Web-PE) Among Active-Duty Military

NCT03337750•University of Pennsylvania

Summary

It is urgent to make evidence-based treatments (EBTs) for military personnel readily accessible in order to meet the growing demand for effective and efficient treatment for posttraumatic stress disorder (PTSD) in a timely manner. Effective EBTs for PTSD are available, but barriers to accessing care can deter military personnel from receiving treatment. Web-treatments represent an innovative way to overcome these barriers. The efficacy of previously developed web-treatments for PTSD appear promising, however, they are not based on treatment protocols with strong empirical support for their efficacy. No study to date has examined web-treatment of PTSD using a well-established treatment program. The purpose of this open trial is to examine the efficacy of 10 sessions of a web-version of Prolonged Exposure (PE), "Web-PE," delivered over 8-weeks in 40 active-duty military personnel and veterans with PTSD who deployed post 9-11. Up to 60 individuals will be consented to obtain data from 40 for analysis. Participants will be assessed at pre-treatment and 1- and 3-months after treatment completion.

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Active-duty military personnel and veterans who have deployed post 9/11
•Seeking treatment for PTSD
•Significant PTSD symptoms as determined by a PCL-5 score greater than or equal to 31
•Has experienced a Criterion A event that is a specific combat-related event or high magnitude operational experience that occurred during a period of recent military deployment
•Able to speak and read English and access to an internet-connected computer
•Indication that the participant plans to be able to participant in the study for the next three months following the first assessment

Exclusion Criteria

•Diagnosis of bipolar disorder or psychotic disorder, as determined by participant self-report)
•Current substance dependence, as determined by participant self-report)
•Diagnosis of a moderate or severe traumatic brain injury, as determined by participant self-report)
•Current suicidal ideation severe enough to warrant immediate attention, as determined by participant self-report)
•Currently engaged in evidence-based treatment for PTSD (e.g. Prolonged Exposure Therapy or Cognitive Processing Therapy), as determined by participant self-report.

Locations (2)

Center for the Treatment and Study of Anxiety, University of Pennsylvania

Philadelphia, Pennsylvania, United States

University of Texas Health Science Center at San Antonio

San Antonio, Texas, United States

Key Dates

Start Date

February 12, 2018

Primary Completion Date

March 27, 2019

Completion Date

February 14, 2020

Last Updated

February 19, 2020

Enrollment

ACTUAL participants

Conditions

Posttraumatic Stress DisorderCombat Disorders

Interventions

Web-PE Therapy

BEHAVIORAL

CIH Stepped Care for Co-occurring Chronic Pain and PTSD

NCT06219408

Chronic PainPosttraumatic Stress Disorder

View study

RECRUITINGNA

Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD

NCT07238192

Posttraumatic Stress Disorder (PTSD)Suicidal Ideation+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 19, 2020Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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An Open-Trial of Web-Prolonged Exposure (Web-PE) Among Active-Duty Military

Inclusion Criteria

Exclusion Criteria

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