Comparison of the Efficacy of Rapid-acting Aspart and Faster Acting Aspart Within the Context of Single-hormone Closed-loop Strategy at Regulating Postprandial Glucose Levels

Exclusion Criteria

• •1. Using a patch-pump (e.g. Omnipod)
• •2. Clinically significant nephropathy, neuropathy or retinopathy as judged by the investigator.
• •3. Recent (\< 6 months) acute macrovascular event e.g. acute coronary syndrome or cardiac surgery.
• •4. Ongoing or planned pregnancy.
• •5. Breastfeeding.
• •6. Severe hypoglycemic episode within two weeks of screening.
• •7. Current use of glucocorticoid medication (except low stable dose and inhaled stable treatment).
• •8. Known or suspected allergy to the trial products or meal contents.
• •9. Other serious medical illness likely to interfere with study participation or with the ability to complete the trial by the judgment of the investigator.
• •10. Failure to comply with team's recommendations (e.g. not willing to eat meals/snacks, not willing to change pump parameters, etc).
• •11. Problems with venous access.