Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

Cohort I: diagnosis of advanced non-small cell lung cancer from 2012-2016;
Cohort II: documented positive driver gene mutations; and diagnosis of advanced non-small cell lung cancer;
Cohort III: diagnosis of advanced non-small cell lung cancer and in immune-therapy;
Cohort IV: diagnosis of advanced non-small cell lung cancer, and with wild-type driver gene or unknown driver gene status;
Cohort V: treated with anti-VEGF drug in first line, diagnosis of advanced non-squamous and non-small cell lung cancer in 6 months before recruit;
Age\>18 years;
Provision of written informed consent.

Observational Cohort Study of Advanced Non-small Cell Lung Cancer (CAPTRA-LUNG)