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Effects of Intraoperative Goal-directed Fluid Therapy (GDFT) on the Postoperative Brain Edema in Neurosurgical Patients With Malignant Supratentorial Gliomas
Whether a fluid protocol aiming for protecting vital organ perfusion or fluid restriction is favorable to post-craniotomy outcomes such as brain edema remains uncertain. To our knowledge, there has been no extensive and quantitative analysis of brain edema following SVV-based GDFT in neurosurgical patients with malignant supratentorial glioma. So the study aims to observe the effect of the stroke volume variation-based GDFT on the postoperative brain edema and decrease the incidence of postoperative complications in neurosurgical patients with malignant supratentorial gliomas.
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
Beijing Tiantan Hospital
Beijing, Beijing Municipality, China
Start Date
November 26, 2018
Primary Completion Date
September 21, 2022
Completion Date
October 31, 2022
Last Updated
March 24, 2023
480
ACTUAL participants
GDFT
OTHER
traditional fluid therapy
OTHER
Lead Sponsor
Beijing Tiantan Hospital
NCT05839379
NCT06962215
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT05588141