Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sienna Biopharmaceuticals
Age
12–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Informed consent/assent and Health Insurance Portability and Accountability Act (HIPAA) authorization
Stable PV for at least 6 months prior to screening
Chronic pruritus of the PV plaques to be present for at least 6 weeks prior to screening
Mild to moderate PV at screening and baseline
Has a target plaque at baseline on the trunk and/or limbs
Subject's plaques are amenable to treatment with a topical ointment medication
Willing and able to comply with the study instructions and attend all scheduled study visits.
Willing to avoid prolonged exposure of the designated treatment plaques to ultraviolet radiation
Females of childbearing potential must have a negative pregnancy test at baseline before randomization and must agree to use highly effective contraception during the study
Men who are sexually active and can father children must agree to use highly effective forms of contraception during the study
You may not be if
Underlying conditions other than psoriasis that, in the opinion of the investigator, currently cause or influence pruritus of the overall skin
Positive hepatitis serology
Thyroid abnormalities that may impact itching
Subjects with spontaneously improving or rapidly deteriorating PV and/or pruritus
Current diagnosis of guttate, erythrodermic, exfoliative, or pustular psoriasis
Active psoriasis or itch affecting the palmar/plantar regions
Subjects with a clinical diagnosis of bacterial infection of the skin
Any major medical illness or symptoms of a clinically significant illness that may influence the study outcome
Any acute chronic medical or psychiatric condition or laboratory abnormality that would make them unsuitable for participation in this study
Known hypersensitivity to the study treatment excipients and /or polyethylene glycol, that contraindicates participation
Currently enrolled in an investigational drug or device study or has used an investigational drug or an investigational device treatment within 30 days of randomization/baseline (Note: Subjects who are enrolled in a long-term follow-up study and are not actively receiving an investigational drug or investigational device treatment may be eligible for participation in this study)
Female who is pregnant or lactating, or is planning to become pregnant during the study
Subjects participating in any previous SNA-120 (and/or CT327) clinical studies
