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HCV Post-Exposure Prophylaxis for Health Care Workers | Clinical Trials | Clareo Health

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HCV Post-Exposure Prophylaxis for Health Care Workers

Hepatitis C Virus Post-Exposure Prophylaxis for Health Care Workers

NCT03313414•Massachusetts General Hospital

Summary

This is an unblinded, observational trial of sofosbuvir-velpatasvir in adult health care workers who are exposed to hepatitis C virus from needlestick injury with hollow-bore needles.

Detailed Description

The goal of this study is to assess the safety and tolerability of the use of sofosbuvir-velpatasvir in the setting of post-exposure prophylaxis among Health Care Workers exposed to HCV from needlestick injury with hollow-bore needles

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Healthcare worker with exposure through needlestick injury with hollow-bore needles to source patients who are HCV positive
•Healthcare worker must be HCV Ab-

Exclusion Criteria

•HCV Ab positive
•HCV Ab negative and HCV RNA greater than 1000 IU/ml
•Active malignancy
•Positive urine pregnancy test

Locations (1)

Massachusetts General Hospital

Boston, Massachusetts, United States

Key Dates

Start Date

August 13, 2019

Primary Completion Date

January 1, 2020

Completion Date

January 16, 2020

Last Updated

January 21, 2020

Conditions

Hepatitis C

Interventions

Sofosbuvir/Velpatasvir Treatment for 14 days

DRUG

Implementing Low-Barrier HCV Treatment in a Jail Setting

NCT06953479

HEPATITIS C (HCV)Incarceration+2 more

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RECRUITINGNA

Project I Test: Implementing HIV Testing in Opioid Treatment Programs

NCT03135886

HIV/AIDSHepatitis C+2 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 21, 2020Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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HCV Post-Exposure Prophylaxis for Health Care Workers

Inclusion Criteria

Exclusion Criteria

Implementing Low-Barrier HCV Treatment in a Jail Setting

Project I Test: Implementing HIV Testing in Opioid Treatment Programs

Persuasive Health Communication Intervention for HIV/HCV

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Acceptability of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users in Non-conventional Structures