Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Tammie L. S. Benzinger, MD, PhD
Age
65–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Male or female participants, at least 65 years of age.
2. Participant is willing to undergo a lumbar puncture (LP) or has previously undergone LP. LP will be conducted under IRB ID 201109100 (PI: Anne Fagan).
3. Participant is able and willing to undergo positron emission tomography (PET) and magnetic resonance imaging (MRI) of the brain.
4. Pre-menopausal women must have a negative urine pregnancy test within 24 hours preceding T807 drug administration.
You may not be if
1. Has any condition that, in the Investigator's opinion, could increase risk to the participant, limit the participant's ability to tolerate the experimental procedures, or interfere with the collection/analysis of the data (for example, participants with severe chronic back pain might not be able to lie still during the scanning procedures).
2. Is deemed likely unable to perform the imaging procedures for any reason.
3. Has a history of Torsades de Pointes or is taking medications known to prolong or may prolong QT interval (refer to study's list of restricted medications).
4. Has known hypersensitivity to T807 or any of its excipients.
5. Contraindications to PET, PET-CT or MR (e.g. electronic medical devices, inability to lie still for long periods) that make it unsafe for the individual to participate.
6. Severe claustrophobia.
7. Currently pregnant or breast-feeding. -
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