Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Great Ormond Street Hospital for Children NHS Foundation Trust
With
University of Kiel
Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Cukurova University
Detailed description and study protocol will be available to individuals on request.
Age
0–18
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
I - For healthy children
All children \<18 years
Normal renal function (eGFR 90-120ml/min/1.73m2 \[calculated by Schwartz formula\] in children \>1 year and serum creatinine \<35μMol/L in children \<1 year)
Weight, height and BMI within 2 SD of normal using WHO growth charts In order to make this study as 'real-life' as possible, free-living UK children on their usual diet and dietary supplementation (including Ca and Vit D), if any, will be included, but analysis will account for medication doses and blood levels.
Children of all ages with an eGFR \<60ml/min/1.73m2, including those on dialysis.
You may not be if
Pre-existing bone disease - inherited or acquired
Fractures in the preceding 6 months
Glucocorticoid therapy in the preceding year, or a lifetime cumulative steroid exposure ≥6 months
Bisphosphonate therapy at any time in the past
Any acute illness in the preceding 2 weeks (when the child is unable to maintain their usual diet or has bed rest)
