Nestle Impact Advanced Recovery in Improving Surgery Recovery in Patients With Head and Neck Cancer

PRIMARY OBJECTIVES: I. Assess the effect of perioperative use of Nestle Impact Advanced Recovery (AR) on the rate of post-operative wound complications within 30 days after major head and neck surgery. SECONDARY OBJECTIVES: I. Assess whether sarcopenia is an independent risk factor for the development of post-operative wound complications. II. Assess whether Nestle IMPACT AR decreases the rate of other post-operative complications such as pneumonia, urinary tract infection, deep vein thrombosis, and clostridium difficile colitis within 30 days of surgery, as well as length of hospital stay. TERTIARY OBJECTIVES: I. Assess changes in muscle metabolic gene expression at the time of surgery associated with sarcopenia and IMAPCT treatment. OUTLINE: Patients are randomized into 1 of 2 groups. GROUP I: Patients receive Nestle Impact AR for 5 days before and after surgery in addition to regular diet. GROUP I: Patients receive regular diet. After completion of study, patients are followed up for 30 days post-surgery.