Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Johns Hopkins University
Age
18–65
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
healthy volunteers 18-65 years of age
Patients diagnosed with recent onset schizophrenia (within 5 years of onset), 18-65 years of age
Patients diagnosed with recent onset bipolar disorder (within 5 years of onset of first mania), 18-65 years of age
screening laboratory tests will be obtained for subjects within a 10 day period prior to the PET study and the results must be within normal limits for gender and age. These tests will be repeated with a 7-day window following the PET study
EKG conducted within 10 day period prior to the PET study. The EKG will be repeated within 7 days following the study.
Subject agrees to return to the Hospital for a follow-up EKG and laboratory testing of blood and urine.
For females of childbearing potential, negative serum pregnancy test within a 10 day period prior to PET study.
You may not be if
history of recent nosocomial infection,
history of chronic neurological disorder, such as multiple sclerosis or epilepsy, or structural,central nervous system (CNS) abnormality such as stroke or arteriovenous malformation,
history of head injury with loss of consciousness \> 1 hour,
history of active substance abuse as defined by substance abuse including alcohol abuse over the 6 months prior to the study,
dependence on benzodiazepine medication
contraindications to MRI scanning to include pacemakers, metallic implants/prosthesis or prohibitive claustrophobia, etc.
contraindications to PET scanning to include pregnancy, etc. For females of childbearing potential, negative serum pregnancy test less than 10 days prior to PET study
ECG demonstrating the patient is not in a sinus rhythm or is having acute ischemia.
any medical condition that in the opinion of the study investigators would constitute a safety risk to the subject.
