Translational Approaches to Septic Cardiomyopathy

Inclusion Criteria

• •At least 18 years of age Admitted to the ICU
• •SEPSIS PATIENTS:
• •Sepsis patients must have:
• •1. Suspected or confirmed infection AND
• •2. Organ dysfunction as defined by a SOFA \>= 2 above baseline (if no baseline data available, SOFA assumed to be 0)
• •OR
• •SEPTIC SHOCK PATIENTS:
• •AFTER INFUSION OF 20ML/KG CRYSTALLOID OR EQUIVALENT, septic shock patients must have:
• •1. Suspected or confirmed infection AND
• •2. Lactate \> 2 mmol/L AND
• •3. Receiving vasopressors