Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
The Cleveland Clinic
The purpose of the project is threefold:
1. To study the natural history of radiation retinopathy using advanced imaging techniques. A combination of macular OCT to evaluate for edema, OCT angiography to evaluate for macular and peri-papillary ischemia and wide-field angiography for peripheral ischemia and leakage. Potential role of OCT angiography in radiation retinopathy will be evaluated by comparison to other eye (control) and FA.
2. Currently there is no consensus on effective management strategy for radiation retinopathy. Patients in the interventional will be prospectively followed to study efficacy of steroids for early treatment of radiation retinopathy while comparing the multimodal therapeutic approach in a randomized trial.
3. Patients in the observational arm will be prospectively followed while comparing the multimodal therapeutic approach in a randomized trial.
Age
18–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Primary uveal melanoma
Primary treatment with plaque brachytherapy
Baseline visual acuity 20/200 or better
Posterior tumor margin \>1.50 mm from the center of the macula
Posterior tumor margin \> 1.50 mm from the closest disc margin
Calculated total dose to center of the macula \>40 Gy
