The First Affiliated Hospital of Guangzhou Medical University
Age
40–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Clinically stable with chronic hypercapnic COPD (baseline arterial carbon dioxide pressure (PaCO2) of 50 mmHg or higher, measured resting in a sitting position and breathing room air without having used NPPV for at least 1 hour)
You may not be if
other lung/pleural diseases or thoracic deformity
severe heart failure (New York Heart Association class IV), severe dysrhythmia
unstable angina, or malignant comorbidity
obesity (BMI ≥ 35 kg/m²)
severe obstructive sleep apnea syndrome
Clareo Health | Efficacy of High-intensity NPPV and Low-intensity NPPV in Patients With Chronic Hypercapnic COPD
