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Keep this study
Lead
Assistance Publique - Hôpitaux de Paris
With
URC-CIC Paris Descartes Necker Cochin
Children aged 5 to 6 years old will be included from the FEPED cohort. The FEPED cohort is a cohort of French pregnant women designed to study the association between vitamin D status during pregnancy and the risk of pre-eclampsia. Vitamin D concentration at first and third trimester of pregnancy as well as in cord blood is available for 1400 women. Investigators will include 200 children born from these women. Children will undergo lung function tests and prick-tests and parents will answer the ISAAC questionnaire that is a standardised questionnaire designed to evaluate asthma and rhinitis symptoms. The main outcome of this study will be specific airway resistance. The investigators will look for an association between specific airway resistance and vitamin D concentration measured during the first trimester of pregnancy in their mothers.
Age
5–6
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
term-born child (gestational age ≥ 37 weeks of post-menstrual age) whose mother was included in the FEPED cohort
measure of vitamin D concentration available at the first and third trimester of pregnancy and in cord blood
cord blood sample available for DNA extraction
child's age between 5 and 6 years old at the time of participation
written informed consent obtained from the legal guardian of the child
health insurance
You may not be if
parent's' refusal
underlying disease that does not allow the performance of lung function tests
Clareo Health | Respiratory Outcome of Children From the FEPED Cohort
