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Early Life Origins of Pediatric and Adult Diseases: Boston Birth Cohort Study
Early life exposures may lead to adverse effects on health in later life. The Boston birth Cohort study is designed to study a broad array of early life factors and their effects on maternal and child health outcomes.
Any woman admitted to the Labor and Delivery floor at the Boston Medical Center (BMC) who delivers a singleton live infant and meets our case (gestational age \<37 weeks or birthweight \<2,500 grams) or control (full term birth with birthweight \>2,500 grams) criteria will be eligible. Postnatal follow-up of enrolled mother-child pair is conducted from birth to age 21 years. The Boston Birth Cohort has high-quality biospecimen collection, and comprehensive epidemiological, clinical, and environmental exposure data via standardized questionnaire interview, measurements, and review of the electronic medical records.
Age
0 - 50 years
Sex
ALL
Healthy Volunteers
No
Boston Medical Center
Boston, Massachusetts, United States
Start Date
October 1, 1998
Primary Completion Date
December 1, 2028
Completion Date
December 1, 2028
Last Updated
September 17, 2025
24,000
ESTIMATED participants
Lead Sponsor
Johns Hopkins Bloomberg School of Public Health
Collaborators
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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