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Keep this study
Lead
University of Cincinnati
Subjects with reduced ejection fraction will be randomized to 8 weeks Yoga training (1 in class session and home practice) vs. no Yoga. They will undergo holter monitoring, cardiac device interrogation, and I-123 mIBG imaging at the beginning and end of the study.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Negative pregnancy test in females
Ejection Fraction \</= 40% assessed by echocardiogram within the last 12 months
Stable dose of heart failure medications including afterload reducing medication such as ACE-I, ARB and hydralazine; beta blockers; digoxin and aldosterone antagonist for at least 4 months and no anticipated changes for 8 weeks. (i.e. no greater than a 50% dose change within the past month)
Has an implantable pacemaker or ICD
NYHA II-IV
You may not be if
pregnant or lactating female
females without a pregnancy test
co-administration of a positive inotrope (i.e. milrinone or dobutamine)
history of significant medical non-compliance
unwilling to adhere to the protocol
Orthopedic limitation making yoga participation difficult
Underlying cardiac rhythm other than sinus rhythm
Recent history within 6 months prior to enrollment of unstable coronary artery disease (unstable angina, recent heart attack, recent revascularization, or decompensated heart failure)
implantation of a cardiac resynchronization therapy device in the past 3 months.
TIA, CVA, or major surgery in the past 3 months
iodine or adreview (123-MIBG) allergy
Clareo Health | The Effect of Yoga on Cardiac Sympathetic Innervation Evaluated by I-123 mIBG
