Inability to provide informed consent

Relative contraindications to LVR, including known pneumothorax, active internal bleeding, unstable hypertension, unstable angina, emphysema, recent barotrauma, or FEV1 (Forced Expiratory Volume, trial 1)/FVC ratio \< 0.7.

Use of EMST or breath stacking \> 3 days/week within 12 weeks of screening

Amyotrophic Lateral Sclerosis-Cognitive Behavioral Scale (ALS-CBS) score predictive of dementia (≤ 10)

Participation in another clinical trial of an intervention in ALS within 30 days of study enrollment or during study enrollment

Lung Volume Recruitment Combined With Expiratory Muscle Strength Training in ALS

What this study is about