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Lead
University of Florida
Determine the skeletal muscle and adipose tissue disposition of prophylactic Cefazolin using microdialysis sampling in a cohort of patients diagnosed with idiopathic scoliosis undergoing posterior spinal fusion (PSF) for administration of Cefazolin by either continuous infusion or intermittent bolus.
Age
12–20
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of idiopathic scoliosis
Planned posterior spinal fusion surgery (PSFS)
Age: 12-20 years old
American Society of Anesthesiology status I or II undergoing posterior spinal fusion for at least 6 levels
No known allergy to cefazolin
You may not be if
Known allergy to cefazolin
Anatomical or other abnormalities that precluded insertion of a microdialysis catheter into the selected paraspinal muscle
Known renal or hepatic insufficiency or failure
Clareo Health | Skeletal Muscle and Adipose Tissue Study
