Safety Assessment of Intravitreal Mesenchymal Stem Cells for Acute Non Arteritic Anterior Ischemic Optic Neuropathy

Exclusion Criteria

• •Giant cell arteritis evidence (clinical history, Erythrocyte sedimentation rate (ESR), C-Reactive Protein)
• •Evidence of any other etiology that may justify the optic neuropathy (even in the non-study eye)
• •History of systemic vasculitis, multiple sclerosis, collagenopathies or previous cancer treatments.
• •Hypersensitivity or allergy to any compound used in the study, including investigational medicinal product (IMP).
• •Positive pregnancy test at baseline
• •Participation in any other research study within 2 months
• •History of uveitis or active ocular inflammation
• •History or evidence of glaucoma or high intraocular pressure ( ≥ 24 mmHg in either eye).
• •Mean opacities or retinal pathologies in the study eye.
• •Any previous vitreous or glaucoma surgery in the study eye
• •Cataract surgery within 3 months in the study eye