Early Use of TIPS With Polytetrafluoroethylene(PTFE) Covered Stents in Cirrhotic Patients With Refractory Ascites

Exclusion Criteria

• •With more than 6 paracenteses within the last 3 months
• •patients expected to receive transplants within the next 6 months or on waiting list
• •Usual contra-indication for TIPS: congestive heart failure NYHA\>III or medical history of pulmonary hypertension, portal vein thrombosis（\>50%）, hepatic polycystosis, intra-hepatic bile ducts dilatation
• •Patient has had previous TIPS placement
• •Severe liver dysfunction by: Prothrombin index \< 40% or total bilirubin \> 50μmol/l
• •Serum creatinine \>133μmol/l
• •Severe hyponatremia \<125mmol / L
• •Uncontrolled sepsis
• •Gastrointestinal hemorrhage within 6 weeks of randomization
• •Known allergy to albumin
• •Pregnant or breast feeding women
• •Refusal to participate or patient unable to receive informations or to sign written informed consent