Treatment Off Gingival Recession Defects Using a Xenogenic Acellular Dermal Matrix Compared to Connective Tissue Graft.

Exclusion Criteria

• •Patient with absolute contra-indication for dental surgery: valvular heart disease at risk of infectious endocarditis, recent myocardal (≤ 12 months), organ transplants, recent placement of a coronary stent (≤ 12 months), transient ischemic attacks recurrent, cardiovascular instability, uncontrolled epilepsy, rheumatic fever.
• •Patient with metabolic bone disease (Paget's disease, osteomalacia, osteogenesis imperfecta)
• •Patient with an ASA score ≥ 3.
• •Patient with absolute contra-indication to dental surgery
• •Patient with severe hematologic disease
• •Patient with I or type II diabetes
• •Patients with previous or current acute illness or severe chronic cardiovascular, renal, hepatic, gastrointestinal, allergic, endocrine, neuro-psychiatric, considered by the investigator to be incompatible with the conduct of the study.
• •Patients treated with retinoids, oral bisphosphonates, oral anticoagulants or anticonvulsants.
• •Patient have or have had cancer of the upper aerodigestive tract treated by radiotherapy.
• •Patient taking a steroidal or non-steroidal anti-inflammatory, anti-cancer or immunosuppressive chemotherapy in the last 6 months.
• •Patient monitoring considered difficult by the investigator.
• •Patient with poor oral hygiene incompatible with oral surgery.
• •Patients with periodontal disease unstabilized
• •Patient with oral dermatitis or adverse occlusion.
• •Patient with an acute or chronic infection of the surgical site (osteomyelitis).
• •Patient with a known allergy to collagen
• •Patient with autoimmune disease
• •Patient with a linguistic or mental incapacity to understand information
• •Patient younger than 45 years old
• •Patient trust under curatorship or judicial protection
• •Patients aged over 45 premenopausal.
• •Patient participating in another clinical study.