Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
The University of Hong Kong
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adults ≥ 18 years of age, male or female.
Histopathologically or cytologically confirmed adenocarcinoma.
Failed ≥ 2 lines of standard therapy which must include a fluoropyrimidine, oxaliplatin and/or irinotecan, administered either as monotherapy or doublets.
ECOG performance status 0 to 2.
Adequate bone marrow reserve.
Absolute neutrophil count \> 1 × 109/L.
Total bilirubin \< 3 × the upper limit of the normal range.
Life expectancy ≥ 12 weeks.
Signed written informed consent form.
You may not be if
Prior malignant disease other than colorectal cancer within 5 years of study entry.
Patients suitable for surgical or locoregional therapies.
Patients unable to swallow oral medications.
Any evidence of brain metastasis (unless the patient is \>6 months from definitive therapy, has a negative imaging study within 4 weeks of study entry and is clinically stable with respect to the tumor at the time of study entry).
Active clinically serious infections (\> grade 2 NCI / CTC Adverse Event version 3.0).
History of allergy to platinum compounds.
Patients who have chronic inflammatory bowel disease and/or bowel obstruction.
Patients who have severe bone marrow failure.
Patients undergoing renal dialysis.
History of HIV infection.
Seizure disorder requiring medication (such as steroids or anti-epileptics).
Women who are pregnant or breast-feeding, or women of child-bearing potential who are unable or unwilling to practice a highly effective means of contraception.
Substance abuse, medical, psychological or social conditions that may interfere with the patient's participation in the study or evaluation of study results.
Clareo Health | Study of Xeloxiri Regimen for Patients With Refractory Metastatic Colorectal Cancer
