Levetiracetam in Early Psychosis

Exclusion Criteria

• •1. Current substance abuse or dependence for substances other than nicotine and THC (i.e., alcohol, amphetamines, barbiturates)
• •1. A positive urine toxic screen (excluding THC, tricyclic antidepressants, or benzodiazepines (if prescribed))
• •2. Moderate or severe cannabis use disorder
• •3. Use of marijuana within the 72 hours prior to MRI scanning by self report
• •2. Diagnosis of major mood disorder or other Axis I disorder other than Schizophrenia, Schizoaffective Disorder or Schizophreniform Disorder
• •3. Current suicidal ideation. Suicidal ideation with intent or plan (indicated by affirmative answers to items 4 or 5 of the suicidal ideation section of the baseline C-SSRS) in the 6 months prior to screening or subjects who represent a significant risk of suicide in the opinion of the Principal Investigator and/or PhD or MD level clinician completing screening visit
• •4. Pregnant, nursing or positive urine pregnancy test
• •5. Significant medical or neurological illness by history or physical exam including seizure disorder, history of loss of consciousness related to head trauma or developmental disorder including mental retardation
• •6. Metal implants, pacemaker, or other metal in the body or medicinal patch
• •7. History of claustrophobia
• •8. Currently taking any antipsychotic medication (within 4 weeks)