Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant

Exclusion Criteria

• •Pregnancy
• •History of documented anaphylaxis or contraindication to any of the study medications
• •Active coronary disease with a positive cardiac stress test
• •History of severe chronic obstructive pulmonary disease (COPD) defined as an FEV1 \< 50% of predicted
• •Serum Creatinine \>/= 2.0 mg/dL
• •Severe hepatic dysfunction accompanied by coagulopathy
• •* Definition:
• •* Known liver Disease AND
• •* INR \> 1.5 (except for patients on anticoagulants) AND
• •* Platelet count \<100,00/ul without other obvious cause
• •Chronic sustained release opioid for \> 2 weeks duration pre op (in the 30 days prior to surgery)
• •Use of toremifene
• •Significant cognitive impairment or documented psychologic impairment
• •Myasthenia gravis or other neuromuscular disease
• •American Society of Anesthesiologists (ASA) Status \> 3