Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Purdue University
Age
30–75
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Inclusion:
Men and women ages 30-75 years old, any race
Moderate CKD, based on the last set of labs done in the past year, defined as:
Glomerular Filtration Rate (GFR) category G3a (eGFR 45-59 mL/min) with A2 or A3 albuminuria or proteinuria by positive dipstick or urine protein/creatinine ratio (UPCR); -or- G3b (eGFR 30-44 mL/min), with or without evidence of albuminuria (any A1-A3) or proteinuria. (Figure 1)
or- Healthy control with no diagnosis or evidence of CKD
Female subjects must be post-menopausal, surgically sterile, or confirmed not pregnant by pregnancy test and not breastfeeding.
You may not be if
Exclusion:
Plans to initiate dialysis within 6 months
Labs based on the last set done in the past year:
Hypercalcemia defined as serum calcium \> 10.5 mg/dL
Hyperkalemic \> 5.5 mg/dL Prescribed a phosphate binder medication
Small bowel resection, bariatric surgery. Medically unstable or poorly controlled hypertension, diabetes, or gastrointestinal disorders in the opinion of the physicians on the study team
Calcitriol, ergocalciferol, cholecalciferol, vitamin D analogs, calcimimetics, PTH analogues, calcium supplements, multivitamins/mineral and other medications that may alter phosphorus metabolism - must be off for at least 6 weeks prior to study
Clareo Health | Phosphorus Absorption in Healthy Adults and in Patients With Moderate Chronic Kidney Disease