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Exploring the reorganization (plasticity) of neuroanatomic networks associated with language and memory in patients with left (or dominant hemisphere) temporal lobe epilepsy using functional MRI (fMRI)
The purpose of this study is to explore the reorganization of neuroanatomic networks associated with language and memory in adult patients with temporal lobe epilepsy (ELT). By using functional MRI, patients will be examined before and after surgery. Cerebral plasticity, defined in terms of intrinsic variables such as the topography of the activated regions, will be explored according to some extrinsic factors such as the age at onset of crises (before or after 5-6 years), whether or not Hippocampal sclerosis, hemispheric predominance of language (left or right).
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
Start Date
June 17, 2009
Primary Completion Date
August 31, 2016
Completion Date
August 31, 2016
Last Updated
April 6, 2017
80
ACTUAL participants
functional MRI
OTHER
Lead Sponsor
University Hospital, Grenoble
Collaborators
NCT06700356
NCT02531880
NCT05871372
Data Source & Attribution
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