Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
King Fahad Medical City
Vitamin D3 has key role in decidualization and implantation of placenta.Vitamin D deficiency is thought to have positive association with pre-eclampsia.Vitamin D deficiency is highly prevalent in some parts of the world and it is not universally screened antenatally. Pre-eclampsia is a known multifactorial pregnancy disorder with significant maternal and perinatal morbidity and mortality. Vitamin D3 has a down-regulating effect on inflammatory pathways and reducing endothelial cell damage.
Investigators want to assess in vitamin D deficient group whether treatment reduces the risk of pre-eclampsia.
Age
20–40
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Confirmed singleton pregnancy of less than 13 completed weeks of gestation at the time of consent.
Planned to receive antenatal care in King Fahad Medical City antenatal clinic.
The ability to provide written informed consent at the first visit.
Low risk pregnancy; and Serum vitamin D3 levels less than \< 25nmol/L.
You may not be if
Mothers with pregnancy with abnormal foetus.
Previous history of hypertension, pre-eclampsia, recurrent miscarriages.
Chronic kidney disease, chronic liver disease, and malignancy.
Clareo Health | Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia