AGE Levels in ER+ Metastatic Breast Cancer Patients Receiving Endocrine Therapy

Inclusion Criteria

• •Must have ER+ breast cancer
• •Metastatic disease; protocol does allow for bone-only disease
• •Must be receiving endocrine therapy
• •Must have completed at last 2 months of current endocrine therapy prior to registration
• •Must have adequate hematologic, renal and hepatic function
• •Prior/concurrent radiation therapy is allowed
• •Prior chemotherapy is allowed, but last dose must have been at least 2 months prior to enrollment
• •May have diabetes, but must not be taking metformin
• •Must be able to swallow and retain oral medication
• •Performance status of 0-2
• •Treated stable brain metastases are allowed, as long as patient does not require steroids or anti-seizure medications
• •Must be informed of the investigational nature of this study and must have the ability to sign informed consent.