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Nonalcoholic fatty liver disease (NAFLD) is an emerging health problem as it can lead to end stage liver failure and cardiovascular complications. Diet play an important role in the development of NAFLD. Many studies have addressed the effects of added fructose on NAFLD. To date, little attention has been paid to the effects of a diet devoid of fructose. Therefore, the investigators aim to study the effects of fructose restriction on hepatic fat accumulation and vascular function using a double-blind randomized placebo-controlled design.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
Maastricht University Medical Center
Maastricht, Limburg, Netherlands
Start Date
January 31, 2017
Primary Completion Date
December 20, 2019
Completion Date
December 20, 2019
Last Updated
February 21, 2020
44
ACTUAL participants
Glucose
DIETARY_SUPPLEMENT
Fructose
DIETARY_SUPPLEMENT
Lead Sponsor
Maastricht University Medical Center
NCT07460960
NCT07237750
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