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Efficacy and Safety of Dexmedetomidine Added to Modified Pectoral's Block in Patient Undergoing Breast Cancer Surgery :A Comparative Study
The Pecs block (pectoral nerves block) is an easy and reliable superficial block inspired by the infraclavicular block approach and the intercostal abdominis plane blocks . Many additives were used in combination with local anesthetics in Pecs block to prolong the postoperative analgesia (fentanyl, dexmedetomidine).
60 patients scheduled for modified radical mastectomy surgery under general anesthesia. Group I (Bupivacaine group): patients underwent modified radical mastectomy were given preoperative ultrasound guided modified Pecs block with 30 mL of 0.25% bupivacaine divided into 10 ml injected between the pectoralis muscles on the interfascial plane, and 20 ml injected between the Pectoralis minor muscle and the serratus muscle.Group II (Bupivacaine + Dexmedetomidine group) : preoperative ultrasound guided modified Pecs block with 30 mL of 0.25% bupivacaine plus Dexmedetomidine (1 µg/kg) divided into 20 ml injected between the pectoralis muscles on the interfascial plane , and 10 ml injected between the Pectoralis minor muscle and the serratus muscle.
Age
18 - 60 years
Sex
FEMALE
Healthy Volunteers
No
South EGYPT cancer institute
Asyut, Egypt
Start Date
February 25, 2017
Primary Completion Date
May 30, 2017
Completion Date
June 15, 2017
Last Updated
February 12, 2026
60
ACTUAL participants
Dexmedetomidine Injection [Precedex]
DRUG
Bupivacaine Injection [Marcaine]
DRUG
Lead Sponsor
South Egypt Cancer Institute
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT05116449