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Effects of Positive End Expiratory Pressure (PEEP) on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy
To investigate the effects of positive end-expiratory pressure (PEEP) on the intracerebral pressure (ICP) and intraocular pressure (IOP) in patients undergoing robot assisted laparoscopic radical prostatectomy (RALRP)
Application of PEEPmay reduce pulmonary complication following RALRP. Meanwhile, it may increase ICP and IOP, which has been debated for decades. Moreover, Trendelenburg position and pneumoperitoneum, which are mandatory for RALRP, may augment elevation of ICP and IOP. This study aims to investigate the effects of PEEP on the ICP and IOP in patients undergoing RALRP.
Age
All ages
Sex
MALE
Healthy Volunteers
Yes
Yonsei University Medical College Gangnam Severance Hospital
Seoul, South Korea
Start Date
January 1, 2017
Primary Completion Date
November 1, 2017
Completion Date
November 1, 2017
Last Updated
January 25, 2017
50
ESTIMATED participants
PEEP group
PROCEDURE
ZEEP group
PROCEDURE
Lead Sponsor
Gangnam Severance Hospital
NCT05691465
NCT04550494
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