Characterization of Fecal Microbiome Changes After Administration of PRIM-DJ2727 in Parkinson's Disease Patients

Inclusion Criteria

• •Diagnosis PD with a Hoehn and Yahr stage of \< 3 in the "Off medicine" state
• •Sexually active male and female subjects of child-bearing potential must agree to use an effective method of birth control during the treatment and follow-up period
• •Female subjects of child-bearing potential must have a negative pregnancy test in the 72 hours before the procedure
• •Subject willing to sign an informed consent form
• •Subject deemed likely to survive for ≥ 1 year after enrolment
• •Subject's attending physician will refer and provide non-transplant care for the subject
• •Subjects must demonstrate adherence to and the ability to maintain a Parkinson's therapy medical regimen that is stable for 90 days before enrolment and participation in the study.