Efficacy and Safety of So-Cheong-Ryong-Tang on Perennial Allergic Rhinitis

Exclusion Criteria

• •1. treatment with nasal/oral corticosteroids within the past month; nasal cromolyn or tricyclic antidepressants within the past two weeks; or nasal/oral decongestants, nasal/oral antihistamines, or antileukotrienes within the past week
• •2. presence of rhinosinusitis (paranasal sinus X-ray demonstrating mucosal thickening, or partial or complete opacification of the paranasal sinuses)
• •3. presence of hypertension (systolic ≥ 180 mmHg or diastolic ≥ 100 mmHg)
• •4. presence of abnormal liver function (aspartate transaminase (AST) or alanine transaminase (ALT) ≥ 100 IU/L) or abnormal renal function (blood urea nitrogen (BUN) ≥ 30 mg/dL or creatinine ≥ 1.8 mg/dL (male), 1.5 mg/dL (female))
• •5. presence of neoplasm, severe systemic inflammation, other systemic disease that affects rhinitis
• •6. history of drug allergy
• •7. history of anaphylaxis for allergic tests
• •8. pregnancy or lactation
• •9. participation of other clinical study within the past 3 months.