A Comparison of Two Socket Sealing Collagen Matrices for Extraction Socket Management

Exclusion Criteria

• •Subjects with healing disorders (i.e., diabetes mellitus, cancer, HIV, bone metabolic diseases) that could compromise wound healing and/ or preclude implant surgery; or who are currently receiving or have received within two months prior to study entry, systemic corticosteroids, immunosuppressive agents, radiation therapy, and/or chemotherapy which could compromise wound healing and preclude periodontal surgery.
• •Subjects taking intramuscular or intravenous bisphosphonates.
• •Subjects who have a known allergy or sensitivity to collagen.
• •Subjects with acute, suppurative lesions with pain, swelling and apical lesions \> 5mm will be excluded, though antibiotic prophylaxis may be employed to reduce infection and provide possible subject reconsideration for inclusion.
• •Heavy smokers/tobacco users defined as those smoking ≥ 10 cigarettes or ≥ 4 cigars or ≥ 4 pipes per day. For non-heavy smokers, smoking ≥ 10 cigarettes or ≥ 4 cigars or ≥ 4 pipes per day is prohibited for the duration of the study.
• •Female subjects who are pregnant or lactating, or who intend to become pregnant during the study duration
• •Subjects participating in other clinical studies involving therapeutic intervention (either medical or dental).
• •Subjects, who in the opinion of the Investigator, for any reason other than those listed above, will not be able to complete the study per protocol.