Autoreactive Anti-Ro/SSA IgE To Determine Primary SjögRen's Syndrome's Disease Activity

Exclusion Criteria

• •Secondary Sjögren's syndrome
• •Other systemic autoimmune disease (e.g. rheumatoid arthritis, AntiNeutrophil Antibodies (ANCA) -associated vasculitis, mixed connective tissue disease…)
• •Incapacity or refusal to sign the informed consent form
• •Incapacity or refusal to perform the follow-up examinations required by the study
• •Has received abatacept, sifalimumab, rontalizumab, anifrolumab, belimumab, Tumor Necrosis Factor (TNF) antagonists or interferon during the 6 months prior to the inclusion
• •Has any current signs or symptoms of active infection