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HORIZONS: a Cohort Study to Explore Recovery of Health and Well-being in Adults Diagnosed With Cancer
The purpose of this study is to invite all people diagnosed with cancer who meet the eligibility criteria to complete questionnaires before their treatment begins and at regular intervals over time to assess the impact of cancer and its treatment on people's lives in the short, medium and long term. We will explore a range of factors to determine their role in both recovery of health and well-being and self-management. Although it is known that people who have had cancer are likely to experience a number of physical and psychological problems as a result of the disease and treatment, it is not known what the 'typical' course of recovery of health and well-being looks like, how long it takes and how this can be influenced. We will determine pathways to recovery of health and well-being following cancer diagnosis (initially breast cancer diagnosed \<50 years, Non-Hodgkin Lymphoma and gynaecological cancers) and identify what factors influence this. This includes assessing the relative importance of the person's illness, personal attributes, perceived burden of treatment, role of the environment they live in, including health / social care and personal networks of support, and their ability and capacity to self-manage. We will identify who is most at risk of problems and what environmental supports and resources people are able to mobilise to support their self-management. We will also explore who has the confidence and ability to manage during and beyond treatment and what factors influence this and whether this leads to earlier problem resolution and restoration of health and well-being. This knowledge will be used to develop and test future supportive interventions to enhance the rapid recovery of health and well-being - our long term aim being to design ways of helping people with cancer in areas we identify as problematic for them.
Age
16 - No limit years
Sex
ALL
Healthy Volunteers
No
Bronglais General Hospital
Aberystwyth, United Kingdom
Monklands Hospital
Airdrie, United Kingdom
Antrim Hospital
Antrim, United Kingdom
William Harvey Hospital
Ashford, United Kingdom
Wansbeck General Hospital
Ashington, United Kingdom
Tameside Hospital
Ashton, United Kingdom
University Hospital Ayr
Ayr, United Kingdom
Ysbyty Gwynedd
Bangor, United Kingdom
Basildon Hospital
Basildon, United Kingdom
Basingstoke and North Hampshire Hospital
Basingstoke, United Kingdom
Start Date
August 1, 2016
Primary Completion Date
December 1, 2020
Completion Date
September 1, 2021
Last Updated
March 17, 2021
3,000
ESTIMATED participants
Lead Sponsor
University Hospital Southampton NHS Foundation Trust
Collaborators
NCT07191730
NCT07465523
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
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