Short Term Oral Iron Supplementation in Systolic Heart Failure Patients Suffering From Iron Deficiency Anemia

Exclusion Criteria

• •History of : active bleeding,infection, malignancy, haematological abnormality, peptic ulcer
• •History of myocardial revascularization (CABG/PCI) within 3 month
• •Acute Coronary Syndrome (ACS), stroke,Transient Ischemic Attack (TIA) within 3 month
• •Know to have allergic reaction to Ferrous sulfate
• •History of intravenous iron administration within 1 month
• •Permanent Pace Maker(PPM)/Implantable Cardiac Defibrillator (ICD)/Cardiac Resynchronization Therapy (CRT)
• •estimated Glomerular Filtration Rate (eGFR) \< 30 ml/min/1.73m2
• •NT-proBNP \> 4000 pg/ml (for patients without baseline data) or decreased level of NT-proBNP \< 30% from baseline
• •Increase level of serum alanine aminotransferase (ALT)/ serum aspartate aminotransferase (AST)\> 3x normal value
• •Moderate to severe primary valvular heart disease
• •Congenital heart disease
• •Right heart failure due to primary pulmonary hypertension, cor pulmonale, Chronic Thrombo-Embolic Pulmonary Hypertension (CTEPH)