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Effect of High-frequency Bio-oxidative Ozone Therapy for Masticatory Muscle Pain: a Double-blind Randomized Clinical Trial
This study investigates the efficacy of bio-oxidative ozone application in the treatment of TMD of muscular origin.
Ozone is a natural pale blue gas that can be found in the atmosphere. Medical grade ozone is a powerful oxidizing agent which can be produced commercially in ozone generators. Ozone can have effects on blood components and positively affect oxygen metabolism, cell energy, immunomodulation and microcirculation.
Age
18 - 60 years
Sex
FEMALE
Healthy Volunteers
No
Start Date
December 1, 2014
Primary Completion Date
June 1, 2017
Completion Date
October 1, 2017
Last Updated
June 16, 2017
60
ACTUAL participants
Ozone
DEVICE
Placebo (for Ozone)
DEVICE
Dental treatment with occlusal splint
DEVICE
Lead Sponsor
Istanbul University
NCT03991728
NCT07317570
NCT06754917
Data Source & Attribution
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