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Active Not RecruitingNANCT02991677

Exercise Effect on Chemotherapy-Induced Neuropathic Pain

Chemotherapy-induced peripheral neuropathy (CIPN) continues to be a serious healthcare concern. It is painful, persistent, resistant to conventional pain therapies, and results in long-term suffering ...

Lead sponsor: Baltimore VA Medical Center•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Baltimore VA Medical Center

Age

21 - 70 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Diagnosis with cancer, stage I-IV
•History of treatment with oxaliplatin, docetaxel, or paclitaxel, either alone or in combination with other agents
•Completion of chemotherapy \> 6 months \< 1 year
•Ability to walk on a treadmill
•Medical clearance from oncologist or primary care provider
•Presence of CIPN per National Cancer Institute Common Toxicity Criteria grade 1-3 (0-no signs/symptoms, 1-minor loss of function, 2-increased symptoms not interfering with activities of daily living (ADLs), 3-severe symptoms interfering with ADL, 4-disabling, and 5 is death)
•Score on Neuropathic Pain Scale \>1
•Age 21-70

Exclusion Criteria

•Denial of CIPN
•Other motor/sensory neuropathy caused by other than chemotherapy (i.e.alcohol-related, autoimmune diseases, diabetes)
•Coronary artery disease
•History of \>1 chemotherapy regimen
•Musculoskeletal conditions which preclude participation in an exercise training program
•Pregnancy
•Regular exerciser, defined as \>90 minutes per week of aerobic exercise and any resistive training

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: August 6, 2024Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhaseNA

Enrollment60

Start dateMar 2018

Last updatedAug 6, 2024

Condition

Cancer, Breast Cancer, Colorectal Cancer, Lung Cancer, Ovarian

Locations shown

Baltimore VA Medical Center

Baltimore, Maryland

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 6, 2024Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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