4. Evidence of inherited disorders of lipid metabolism,
5. History of Cancer within the last 5 years,
6. Human immunodeficiency virus (HIV) antibody positive,
7. Patients with solid organ transplants,
8. Unstable angina or NY heart association class II failure or above,
9. Gastrointestinal disease specifically GI motility disorders,
10. Unstable neuropsychiatric disease including major depression/anxiety, eating disorder such as bulimia or anorexia,
11. End stage renal or hepatic disease,
12. Autoimmune disorders (e.g. SLE),
13. Prior bariatric surgery,
14. A history or current alcohol/substance abuse or nicotine containing products or illicit drugs of abuse during the preceding 6 months,
15. Treatment within one month with sedative hypnotic medications (benzodiazepines, barbiturates), or over the counter sleeping aids
16. Women: any selective estrogen receptor modulator or aromatase inhibitor Men:
androgen ablation/deprivation hormonal therapies
17. Any medical condition, which in the opinion of the investigator would make the patient unsuitable for recruitment, or could interfere with the patient participating in or completing the protocol
18. Any previous adverse events or allergic reactions to acetaminophen
19. Unwilling or unable to consent for the study.
Clareo Health | Role of Gastrointestinal Microbes on Digestion of Resistant Starch and Tryptophan Availability to Humans