The Effect of Isotretinoin on the Etonogestrel Contraceptive Implant

Inclusion Criteria

• •Have a secondary form of non-hormonal contraception or abstain during isotretinoin therapy and four weeks afterwards
• •Have at least two negative pregnancy tests at least 19 days apart prior to initiating isotretinoin therapy
• •Have normal baseline laboratory evaluation including liver function tests, basic metabolic panel, and complete blood count
• •Willing to abstain from taking any Vitamin A supplement during the study period
• •Have a Body Mass Index (BMI) \>= 18.5