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Hypoxic Preconditioning on Patients | Clinical Trials | Clareo Health

COMPLETEDNA

Hypoxic Preconditioning on Patients

The Effects of Intermittent Whole-body Hypoxic Preconditioning on Patients With Carotid Artery Stenosis

NCT02966418•Hua Yan

Summary

The purpose of this study is to study the effects of intermittent whole-body hypoxic preconditioning on patients with carotid artery stenosis.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Informed written consent from the patient.
•2. Han nationality, age \>18 years.
•3. Carotid artery stenosis on at least one side, measuring more than 70% by ultrasonic detection and requiring carotid artery stenting or a carotid endarterectomy.
•4. Long-term residence at an altitude of \<100 m (the altitude of Tianjin is 2-5 m).
•5. Not having been to an altitude ≥1500 m in two years.

Exclusion Criteria

•1. Planned vessel sacrifice as the primary modality for ischemic cerebrovascular treatment.
•2. Systemic blood disease before intervention.
•3. Regular physical activity exercise: frequency \>1 time/week, duration \>20 min.
•4. History of brain disease or history of stroke or transient ischemic attack within the previous six months.
•5. History of heart, liver, kidney or lung disease.
•6. History of hypertension and poor blood pressure control, with blood pressure \>160/90 mmHg.
•7. Pregnancy.

Locations (1)

Tianjin HuanHu Hospital

Tianjin, Tianjin Municipality, China

Key Dates

Start Date

January 1, 2017

Primary Completion Date

December 1, 2017

Completion Date

December 1, 2017

Last Updated

March 1, 2018

Enrollment

ACTUAL participants

Conditions

Hypoxic PreconditioningCarotid Artery StenosisIschemic Cerebrovascular Disease

Interventions

Mild Hypoxia Preconditioning

PROCEDURE

Sham preconditioning

PROCEDURE

Clinical Evaluation of New Biomarkers for Ischemic Cerebrovascular Disease

NCT06890702

Ischemic StrokeIschemic Cerebrovascular Disease

View study

RECRUITINGNA

Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)

NCT06936176

Carotid Artery Stenosis

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RECRUITING

Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)(Extended Follow-Up)

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 1, 2018Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Hypoxic Preconditioning on Patients

Inclusion Criteria

Exclusion Criteria

Clinical Evaluation of New Biomarkers for Ischemic Cerebrovascular Disease

Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)

Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)(Extended Follow-Up)

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