AMPLATZER™ Cardiac Plug Observational Post-Approval Study

Exclusion Criteria

• •1. Patient who is unable to comply with the follow-up schedule
• •2. Patient with the presence of intracardiac thrombus
• •3. Patient with active endocarditis or other infections producing bacteraemia
• •4. Patient who has low risk of stroke (CHA2DS2-VASC score is 0 or 1) or low risk of bleeding (HAS-BLED score\<3)
• •5. Patient where placement of the device would interfere with any intracardiac or intravascular structures
• •6. Patient who is under medical conditions not appropriate to participate in the study in the opinion of the investigator
• •7. Patient with LAA anatomy that does not accommodate a device per the sizing guidelines
• •8. Patient who has a life expectancy of less than 2 years due to any condition
• •9. Patient who are currently participating in a clinical investigation that includes an active treatment arm
• •10. Patient who already had a left atrial appendage closure device implanted prior to the study