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Postoperative Behavior in Children: A Comparison of Inhalation Anesthesia (Sevoflurane) Versus Total Intravenous Anesthesia (TIVA)
The aim of this study is to investigate long-lasting or later behavioral changes in children in the context of different anesthesia techniques (Inhalation anesthesia vs. TIVA)
The process of surgery and anaesthesia can be an extremely frightening and stressful event for a child, and is frequently followed by negative postoperative behavioural changes. This Event could be associated with poor postoperative outcome and long term behavior problems like anxiety, eating or sleeping disorders. The aim of this study is to investigate long-lasting or later behavioral changes in children in the context of different anesthesia techniques (Inhalation anesthesia vs. TIVA). After anesthesia initiation, anesthesia maintenance should be done with sevoflurane or Tiva. The effect of behavioral changes in children in the context of anesthesia techniques should be evaluate by post hospitalisation behavior and Strengths and Difficulties Questionnaire at first, second and fourth week. Early postoperative problems like postoperative nausea and vomiting, pain level, pain therapy and postoperative awareness should be evaluate too.
Age
2 - 10 years
Sex
ALL
Healthy Volunteers
Yes
Dr. Philipp Buehler
Zurich, Switzerland
Start Date
January 22, 2018
Primary Completion Date
June 4, 2024
Completion Date
June 4, 2024
Last Updated
December 19, 2024
500
ACTUAL participants
TIVA
PROCEDURE
Sevoflurane
PROCEDURE
Lead Sponsor
University Children's Hospital, Zurich
NCT06984809
NCT06587230
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