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Study With Healthy Japanese and Non-Asian Participants With BMS-986231 | Clinical Trials | Clareo Health

COMPLETEDPHASE1

Study With Healthy Japanese and Non-Asian Participants With BMS-986231

A Randomized, Double-Blind, Placebo-controlled, Single Continuous Intravenous Infusion Study of BMS-986231 to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Healthy Japanese and Non- Asian Participants

NCT02932969•Bristol-Myers Squibb

View on ClinicalTrials.gov

Summary

The purpose of this Phase 1 study is to evaluate the safety, tolerability, PK, and pharmacodynamics (PD) of BMS-986231 in healthy Japanese and Non-Asian participants. There is no formal hypothesis to be statistically tested.

Eligibility

Age

18 - 40 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Ancestry
•* First generation Japanese
•* Non-Asian with grandparents and parents of non-Asian descent
•Body weight greater than or equal to 45kg and less than or equal to 110kg
•Women of childbearing potential have specific birthcontrol methods
•Males sexually active with women of childbearing potential have specific birthcontrol methods

Exclusion Criteria

•History of chronic illness
•Chronic headaches
•Recurrent dizziness
•Personal or family history of heart disease
•Personal history of bleeding diathesis

Locations (1)

West Coast Clinical Trials, Llc

Cypress, California, United States

Key Dates

Start Date

October 4, 2016

Primary Completion Date

May 26, 2017

Completion Date

May 26, 2017

Last Updated

May 31, 2017

Enrollment

ACTUAL participants

Conditions

Heart Decompensation, Acute

Interventions

BMS-986231

DRUG

BMS-986231 Placebo

DRUG

POCUS-Guided Diuresis for Decompensated Heart Failure

NCT06921603

Heart Decompensation, AcuteAcute Kidney Injuries

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 31, 2017Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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