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Low Pulse Amplitude Seizure Therapy (LAP-ST Study) | Clinical Trials | Clareo Health

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Low Pulse Amplitude Seizure Therapy (LAP-ST Study)

NCT02928159•Behman Hospital

View on ClinicalTrials.gov

Summary

This study assesses the feasibility of a full course of Low Pulse Amplitude-Seizure Therapy (LAP-ST) (primary outcome).

Detailed Description

This is hypothesized to increase stimulation focality, thus minimizing cognitive side effects compared to conventional ECT. The study will enroll 22 patients recruited from the Behman Hospital, Cairo, Egypt. Patients referred to ECT service in the Behman Hospital who are clinically indicated to do ECT for major depressive episode of a mood disorder or psychotic episode of a primary psychotic disorder will be approached. Eligible participants who signed informed consent will be included to receive a course of Right Unilateral Ultrabrief LAP-ST.

Eligibility

Age

20 - 80 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. ECT clinically indicated
•2. Males or females over 22 to 80 years of age
•3. Use of effective method of birth control for women of child-bearing capacity
•4. Patient is medically stable
•5. Capacity of patient to fully participate in the informed consent process as evaluated by their clinician

Exclusion Criteria

•1. Current unstable or serious medical condition, or any co-morbid medical condition that substantially increases the risks of ECT
•2. History of conditions that may make ECT unsafe such as metal in the head, or a skull defect
•3. Female patients who are currently pregnant or plan to be pregnant during the study

Key Dates

Start Date

April 1, 2013

Primary Completion Date

June 1, 2015

Completion Date

June 1, 2015

Last Updated

October 10, 2016

Enrollment

ACTUAL participants

Conditions

Mood DisordersSchizophrenia Spectrum and Other Psychotic Disorders

Interventions

Mecta spectrum 5000Q device

DEVICE

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

NCT06740383

Schizophrenia Spectrum and Other Psychotic DisordersSchizophrenia+5 more

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RECRUITINGNA

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DepressionSuicide+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 10, 2016Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Low Pulse Amplitude Seizure Therapy (LAP-ST Study)

Inclusion Criteria

Exclusion Criteria

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

Suicide Specific Rumination in Veterans

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