Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis, Asthma and Allergic Rhinitis
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Lead
Nantes University Hospital
The primary endpoint will be the highlight of a quantitative reduction of double positive T cells (CD4 + / CD8 +) the specific F prausnitzii peripheral blood in patients with allergic asthma, allergic rhinitis and atopic dermatitis compared to samples from a control sample collection made available by the laboratory BIOFORTIS® located near Nantes University of Nantes.
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
non smoker
BMI \<30kg/m²
No contraindication to prick-test
Inform consent signed for genetics
belong to a social security scheme
patients with allergic rhinitis or atopic dermatitis or with allergic asthma
You may not be if
major or major incapable protected
antimicrobial treatment (antibiotic, antifungal or antiviral)
in contact with an MDR bacteria
has received or is receiving specific immunotherapy
History of cancer of the hematopoietic system
antecedent acquired immune deficiency with HIV
congenital immunodeficiency
inflammatory bowel disease
autoimmune disease and / or inflammatory
solid organ transplant or hematopoietic cells
addict
pregnant or of childbearing age without effective contraception
failure of acute or chronic severe organ
hardly speak French and / or difficult to understand French
Clareo Health | Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis, Asthma and Allergic Rhinitis